2-(BROMOMETHYL)BENZENEBORONIC ACID PINACOL ESTER

2-(BROMOMETHYL)BENZENEBORONIC ACID PINACOL ESTER - Names and Identifiers

Name	(2-Bromomethylphenyl)boronic acid, pinacol ester
Synonyms	2-[2-(Bromomethyl)phenyl]-4,4,5,5-tetra (2-BROMOMETHYLPHENYL)BORONIC ACID, PICOL ESTER (2-BROMOMETHYLPHENYL)BORONIC ACID, PINACOL ESTER 2-(BROMOMETHYL)BENZENEBORONIC ACID PINACOL ESTER (2-Bromomethylphenyl)boronic acid, pinacol ester 2-(Bromomethyl)benzeneboronicacidpinacolcyclicester 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl Bromide 2-(2-(Bromomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-[2-(bromomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-[2-(Bromomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl bromide
CAS	377780-72-8
InChI	InChI=1/C13H18BBrO2/c1-12(2)13(3,4)17-14(16-12)11-8-6-5-7-10(11)9-15/h5-8H,9H2,1-4H3

2-(BROMOMETHYL)BENZENEBORONIC ACID PINACOL ESTER - Physico-chemical Properties

Molecular Formula	C13H18BBrO2
Molar Mass	297
Density	1.26±0.1 g/cm3(Predicted)
Melting Point	78-80°C
Boling Point	360.6±25.0 °C(Predicted)
Flash Point	171.9°C
Solubility	Chloroform (Sparingly)
Vapor Presure	4.57E-05mmHg at 25°C
Appearance	solid
Color	white to off-white
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.524

2-(BROMOMETHYL)BENZENEBORONIC ACID PINACOL ESTER - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	2
TSCA	No
Hazard Note	Irritant/Keep Cold

2-(BROMOMETHYL)BENZENEBORONIC ACID PINACOL ESTER - Introduction

(2-Bromometylphenyl) boronic acid, pinacol ester is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White solid
-Molecular formula: C14H19BO3Br
-Molecular weight: 309.12g/mol
-Melting point: 47-48 degrees Celsius
-Boiling point: 361.7 degrees Celsius (expected)

Use:
- (2-Bromomethylphenyl)boronic acid, pinacol ester is commonly used in organic synthesis, especially in metal-catalyzed coupling reactions. It can be used as a source of phenylboronic acid groups to synthesize other functional compounds.
-Specific applications include catalysts, organometallic chemistry and pharmaceutical research.

Preparation Method:
- (2-Bromometylphenyl) boronic acid, the preparation of pinacol ester can be achieved by a variety of methods. One common method is to react phenylboronic acid with 2-bromoethyl bromide to produce 2-bromoethylphenylboronic acid. This product is then reacted with ethanol and sodium to give (2-Bromomethylphenyl)boronic acid, pinacol ester.

Safety Information:
- (2-Bromomethylphenyl)boronic acid, pinacol ester is a chemical that requires proper handling and storage. In use or contact should comply with the chemical laboratory safety procedures.
-It may be harmful to human health and the environment, so inhalation, ingestion or contact with skin and eyes should be avoided. Appropriate personal protective equipment such as goggles, gloves and protective clothing should be worn during operation.
-During processing, please ensure proper ventilation and store it in a dry, cool place, away from fire and oxidants. When no longer required, disposal shall be carried out in accordance with local regulations.

Please read the relevant chemical safety information carefully before use and follow the correct operation method. If you need further information on specific applications and experimental conditions, please consult the relevant literature or consult a professional.

Last Update：2024-04-09 20:49:11